This article in Scientific American Mind is very interesting. I know from reading John C. Lilly that therapists in the USA 1950s - mid 60s used strict guidelines to use LSD. They would actually give the drug and then stay with you to monitor the effects one on one.
I would urge further research because this is based on research that was carried out whilst LSD was legal to use.
To those unfamiliar with the situation in N. Ireland this may sound trivial. The war in N. Ireland is fought between those loyal to London who want to stay in the United Kingdom and those who want a united Ireland.
At the start of World War II Churchill was terrified at the idea that the Republic of Ireland might become invaded by the Germans, the Germans would then control strategically vital atlantic facing ports.
Churchill made an offer to De Valera that if the British were allowed to use the ports in Republic of Ireland that after the war he would give N. Ireland back to Ireland. This is from 'Battle of Britain' by James Holland. I was quite shocked.